Volume 11, Number 1, 2, 3 & 4, January - December, 2023 |
Dalili Mohammed Shabai, Abubakar Mustapha Jamda, Mohammed Basheer Abdulrahman |
This study set out to determine the relationship between microalbuminuria and immunosuppression in treatment naïve HIV seropositive patients. 200 consecutively selected, treatment naïve HIV patients seen in the HIV counseling and testing unit of the Faith Alive Foundation Hospital, Jos, were evaluated for renal disease and immunosuppression: Urinary albumin, urinary creatinine, and CD4 count were analyzed using standard methods. Of the 200 treatment naïve HIV patients evaluated, microalbuminuria was present in 39(19.5%). The difference for the mean values of urinary albumin excretion, (182.30+54.30) p(0.006), was statistically significant. On the other hand, the mean values for the urinary creatinine, (11.70+5.20) p (0.60), was not statistically significant. The difference between the mean values of the albumin/creatinine ratio, (1.80+1.20) p (0.001), was statistically significant. The mean value of microalbuminuria in the immunosuppressed (CD4 count of <200/mm3) was70.30%, while the mean values of immunosuppressed patients without microalbuminuria was 0.70% p (0.00) was statistically significant. his study revealed a direct relationship between microalbuminuria and immunosuppression. The means the immunosuppressed treatment naïve HIV patients showedincreased urinary albumin excretion. Therefore, HIV positive immunosuppressed patients should be more frequently screened for microalbuminuria to prevent them from progressing to end stage renal disease. |
10.47837/cmj.19770126.nma.2017512163 |
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