Volume 11, Number 1, 2, 3 & 4, January - December, 2023 |
Ibrahim KG, Umar ZU |
The global epidemic of metabolic syndrome (MetS) constitutes a major public health concern as it affects both the developed and the developing nations, and cuts across all age groups. MetS is a cluster of several risk correlates of cardio-metabolic diseases that predispose to the development of cardiovascular disease and type 2 diabetes mellitus. Despite being a huge problem, no single standalone treatment for MetS exists. Current treatment modalities target the individual risk factors with pharmacotherapy that usually has to be taken for life. In addition to the burden of cost and problems with drug compliance, there is usually the possibility of cumulative toxic side effects from the medications Natural products and herbal medicines have been speculated to have a better safety profile and are more available and affordable. Cucumis sativus L., commonly known as cucumber, belongs to the family Cucurbitaceae which grows both as a wild and cultivated species in the tropics that is usually consumed either raw or cooked as a vegetable. It has historically been recognised and used as a laxative, anthelminthic, and antipyretic, treatment for eye diseases and scorpion stings. Research has shown that the vegetable plant has antioxidant, anti-inflammatory and cytotoxic effects. In this narrative review, we highlight the beneficial effects of C. sativus against the components of MetS to make a case for its consideration as a holistic natural treatment option for the syndrome, thus, reducing the risks associated with the prolonged use of orthodox medications. |
10.47837/CMJ.2022102.9 |
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